Begin by downloading POVME 2.0. An example input file is included with the download (in the 'examples' directory). This input file is heavily commented and may be even more useful that the information provided on this website.
If you use POVME in your work, please cite:
- Durrant, J. D., C. A. de Oliveira, et al. (2011). "POVME: An algorithm for measuring binding-pocket volumes." J Mol Graph Model 29(5): 773-776.
- Durrant, J.D., L. Votapka, J. Sørensen, and R. E. Amaro (2014). "POVME 2.0: An Enhanced Tool for Determining Pocket Shape and Volume Characteristics." J. Chem. Theory Comput. 10(11):5047-5056.