# SI2012 Mesoscale Modeling of Cardiac Myocytes

### From NBCRwiki

#### Monday

**Use of Subcell in Mesoscale Simulation of Cardiac Myocyte Calcium Dynamics** Instructor: Pete Kekenes-Huskey, Ph.D., Anushka Michailova, Ph.D.

#### Tuesday

**Segmentation, Mesh Generation and Refinement using GAMer/Blender Interface** Instructors: Pete Kekenes-Huskey, Ph.D.

This session starts with a brief introduction of segmentation of reconstructed EM images of mouse to obtain a realistic sub-cellular geometry. The rest of the session will be used to show how the mesh can be improved using GAMer within the GUI of Blender. Volumetric meshes which can be used in finite element simulations will finally be generated. Simple Blamer Tutorial Talk Tutorial

#### Wednesday

**The use of the general reaction-diffusion solver: SubCell** Instructor: Pete Kekenes-Huskey, Ph.D., Anushka Michailova, Ph.D.

SubCell provides a high level interface to declare and solve general reaction-diffusion equation on unstructured meshes. SubCell is based on the finite element library of FEniCS.

#### Thursday

**From Meshing to Model Building to Simulation of CICR using realistic models of cardiac myocytes** Instructors: Zeyun Yu, Ph.D., Anushka Michailova, Ph.D.

This session introduces computational approaches to image pre-processing and boundary segmentation, and new developments of surface/volumetric mesh generation and quality improvement. We will also discuss finite element simulation of cardiac myocytes using realistic models extracted from imaging data.