SI2007 Computational Cardiac Electrophysiology and Mechanics
From NBCRwiki
General Information
Time: 9 am to 12 pm
Location: Room 4004, Atkinson Hall
Suggested Reading Links to relevant literature
Schedule
- Tuesday: Introduction to Multi-Scale Modeling of the Heart
- Instructors: Andrew McCulloch, Ph.D., Stuart Campbell, Fred Lionetti
- PART I
- Cardiac anatomy and structure
- Cardiac cycle
- Ventricular mechanics and cardiac muscle contraction
- Cardiac electrophysiology
- Excitation-contraction coupling and its regulation
- PART II
- Intracellular diffusion of second messengers – cAMP, Ca
- Reaction-diffusion equation
- Introduction to the finite element method for 2nd order PDEs
- Getting set up with Continuity 6.3
- A simple reaction-diffusion model with Continuity 6.3
- Lecture notes on cardiac myocyte modeling (ppt)
- Lecture notes on cardiac myocyte modeling (pdf)
- Simple Biotransport Example
- Wednesday: Finite Element Discretization and Anatomic Mesh Fitting
- Instructors: Andrew McCulloch, Ph.D., Stuart Campbell, Fred Lionetti
- Steps in the Finite Element Method
- Finite Element Interpolation and Basis Functions
- Least Squares Anatomic and Field Fitting
- Lecture notes on meshes and anatomic fitting (ppt)
- Lecture notes on meshes and anatomic fitting (pdf)
- Wednesday's Exercises:
- Thursday: Monodomain Modeling in Cardiac Electrophysiology
- Instructors: Roy Kerckhoffs, Ph.D., Fred Lionetti, Andrew McCulloch, Ph.D.
- Ionic Models of Cardiac Myocyte Electrophysiology
- Finite Element Methods for Action Potential Propagation
- Lecture notes on monodomain modeling (ppt)
- Lecture notes on monodomain modeling (pdf)
- Exercises
- Friday: Modeling Cardiac Biomechanics and Electromechanics
- Instructors: Andrew McCulloch, Ph.D., Roy Kerckhoffs, Ph.D., Stuart Campbell, Fred Lionetti
- Modeling Ventricular Wall Mechanics
- Constitutive Models of Cardiac Muscle
- Galerkin FEM for ventricular stress analysis
- Newton’s method
- Ventricular-Vascular Coupling
- Lecture notes on biomechanics modeling (ppt)
- Lecture notes on biomechanics modeling (pdf)